@article { ISI:000369941600015,
	title = {Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerful beta-galactosidase inhibitors and low concentration activators of G(M1)-gangliosidosis-related human lysosomal beta-galactosidase},
	journal = {BIOORGANIC \& MEDICINAL CHEMISTRY LETTERS},
	volume = {26},
	number = {5},
	year = {2016},
	month = {MAR 1},
	pages = {1438-1442},
	abstract = {From an easily available partially protected formal derivative of 1-deoxymannojirimycin, by hydroxymethyl chain-branching and further elaboration, lipophilic analogs of the powerful beta-D-galactosidase inhibitor 4-epi-isofagomine have become available. New compounds exhibit improved inhibitory activities comparable to benchmark compound NOEV (N-octyl-epi-valienamine) and may serve as leads towards improved and more selective pharmacological chaperones for G(M1)-gangliosidosis. (C) 2016 Elsevier Ltd. All rights reserved.},
	issn = {0960-894X},
	doi = {10.1016/j.bmcl.2016.01.059},
	author = {Thonhofer, Martin and Weber, Patrick and Santana, Andres Gonzalez and Fischer, Roland and Pabst, Bettina M. and Paschke, Eduard and Schalli, Michael and Stuetz, Arnold E. and Tschernutter, Marion and Windischhofer, Werner and Withers, Stephen G.}
}
