@article { ISI:000349323500043,
	title = {Understanding viral neuraminidase inhibition by substituted difluorosialic acids},
	journal = {CHEMICAL COMMUNICATIONS},
	volume = {51},
	number = {14},
	year = {2015},
	pages = {2933-2935},
	abstract = {Mechanism-based inhibition of influenza neuraminidases by difluorosialic acids (DFSA) is not only rendered highly specific by incorporation of 4-amino or 4-guanidine substituents but also the half-life for reactivation is greatly increased. Measurement of rate constants for spontaneous hydrolysis of a series of such substituted DFSAs reveals, surprisingly, that inherent inductive effects play very little role in this rate reduction and that interactions with the enzyme are more important.},
	issn = {1359-7345},
	doi = {10.1039/c4cc08256g},
	author = {Weck, S. and Robinson, K. and Smith, M. R. and Withers, S. G.}
}
