@article { ISI:000276238500001,
	title = {Synthesis of lipophilic 1-deoxygalactonojirimycin derivatives as D-galactosidase inhibitors},
	journal = {BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY},
	volume = {6},
	year = {2010},
	month = {MAR 1},
	pages = {21},
	abstract = {N-Alkylation at the ring nitrogen of the D-galactosidase inhibitor 1-deoxygalactonojirimycin with a functionalised C(6) alkyl chain followed by modification with different aromatic substituents provided lipophilic 1-deoxygalactonojirimycin derivatives which exhibit inhibitory properties against beta-glycosidases from E. coli and Agrobacterium sp. as well as green coffee bean alpha-galactosidase. In preliminary studies, these compounds also showed potential as chemical chaperones for GM1-gangliosidosis related beta-galactosidase mutants.},
	issn = {1860-5397},
	doi = {10.3762/bjoc.6.21},
	author = {Schitter, Georg and Scheucher, Elisabeth and Steiner, Andreas J. and Stuetz, Arnold E. and Thonhofer, Martin and Tarling, Chris A. and Withers, Stephen G. and Wicki, Jacqueline and Fantur, Katrin and Paschke, Eduard and Mahuran, Don J. and Rigat, Brigitte A. and Tropak, Michael and Wrodnigg, Tanja M.}
}
