@article { ISI:000180748300001, title = {Synthesis with glycosynthases: Cello-oligomers of isofagomine and a tetrahydrooxazine as cellulase inhibitors}, journal = {AUSTRALIAN JOURNAL OF CHEMISTRY}, volume = {55}, number = {12}, year = {2002}, pages = {747-752}, abstract = {Isofagomine and a carbohydrate-like tetrahydrooxazine, as their N-benzyloxycarbonyl derivatives, have been subjected to a glycosynthase in the presence of alpha-D-glucopyranosyl fluoride as a glucosyl donor. In each case, after protecting group removal, a mixture of 1, 4-beta-linked di-, tri-, and tetra-{\textquoteright}saccharides{\textquoteright} was obtained. These novel oligosaccharide derivatives were tested as inhibitors of the endo-glycanase Cex from Cellulomonas fimi. Affinities increased progressively as additional D-glucosyl residues were incorporated, which is consistent with the known substrate specificity of this enzyme.}, issn = {0004-9425}, doi = {10.1071/CH02165}, author = {Macdonald, JM and Stick, RV and Tilbrook, DMG and Withers, SG} }