@article { ISI:000328231600030,
	title = {Assembly of a Key Dienic Intermediate for Tetrodotoxin via a Machetti-DeSarlo Reaction},
	journal = {JOURNAL OF ORGANIC CHEMISTRY},
	volume = {78},
	number = {23},
	year = {2013},
	month = {DEC 6},
	pages = {11901-11910},
	abstract = {A route to a racemic diene intermediate for the synthesis of tetrodotoxin is described. Key steps of the sequence leading to such a compound include the oxidative amidation of a phenol, a Cu(II)-catalyzed cyclocondensation of a nitroketone with an olefin (Machetti-DeSarlo reaction), and a nucleophilic fragmentation of the resulting isoxazoline. Several unusual reactions encountered in the course of this study are thoroughly discussed.},
	issn = {0022-3263},
	doi = {10.1021/jo401960p},
	author = {Chau, Jaclyn and Xu, Sanjia and Ciufolini, Marco A.}
}
