@article {2775,
	title = {THE SYNTHESIS AND X-RAY STRUCTURES OF THE GEOMETRIC ISOMERS OF 1-AMINO-1,2-CYCLOPENTANEDICARBOXYLIC ACID},
	journal = {Canadian Journal of Chemistry-Revue Canadienne De Chimie},
	volume = {71},
	number = {1},
	year = {1993},
	note = {ISI Document Delivery No.: KN060Times Cited: 5Cited Reference Count: 9},
	month = {Jan},
	pages = {76-83},
	type = {Article},
	abstract = {The geometric isomers of 1-amino-1,2-cyclopentanedicarboxylic acid were isolated as the hydrolysis products of 2-cyclopentanecarboxylic acid-5,5{\textquoteright}-hydantoin. The hydantoin ester was formed from ethyl -2-oxocyclopentanecarboxylate via a Bucherer-Bergs reaction. Hydrolysis of the hydantoin at elevated temperatures gave a mixture of trans- and cis-1-amino-1,2-cyclopentanedicarboxylic acids indicating epimerization during hydrolysis. The trans product has not been described previously and the cis not extensively characterized. X-ray crystallography reveals that both isomers are zwitterionic in the solid state and the cis isomer molecules are linked by unusually strong hydrogen bonding. Structures were confirmed by C-13 NMR, X-ray crystallography, and elemental analysis. Physical data are also presented.},
	keywords = {BUCHERER-BERGS, NEURONS, STEREOCHEMISTRY, STRECKER REACTIONS},
	isbn = {0008-4042},
	url = {<Go to ISI>://A1993KN06000011},
	author = {Curry, K. and McLennan, H. and Rettig, S. J. and Trotter, J.}
}
