|Title||TRIDIDEMNIC ACID-A AND ACID-B, AROMATIC ALKALOIDS FROM THE NORTHEASTERN PACIFIC ASCIDIAN TRIDIDEMNUM SP|
|Publication Type||Journal Article|
|Year of Publication||1992|
|Authors||De Silva, ED, Miao, SC, Andersen, RJ, Schultz, LW, Clardy, J|
|Type of Article||Article|
|Keywords||ALKALOID, ASCIDIAN, TRIDIDEMNUM|
Two new aromatic alkaloids, trididemnic acids A (1) and B (2), have been isolated from the marine ascidian Trididemnum sp. The structures of 1 and 2 were solved by spectroscopic analysis of their permethylated derivatives 4 and 5. Single crystal x-ray diffraction analysis of 4 confirmed the structures. An interesting retro-Fries rearrangement reaction, involving the conversion of 3 to 8 under bromination conditions, was also discovered.
|URL||<Go to ISI>://A1992HV88700002|