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Total Synthesis and Complete Structural Assignment of Thiocillin I

TitleTotal Synthesis and Complete Structural Assignment of Thiocillin I
Publication TypeJournal Article
Year of Publication2011
AuthorsAulakh, VS, Ciufolini, MA
JournalJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume133
Pagination5900-5904
Date PublishedAPR 20
ISSN0002-7863
Abstract

The total synthesis of the thiopeptide antibiotic, thiocillin I, is described. This work unequivocally defines the full structure (constitution and configuration) of the natural product as 1.

DOI10.1021/ja110166x