Research & Faculty

Default Header Image

A Perspective - can copper complexes be developed as a novel class of therapeutics?

TitleA Perspective - can copper complexes be developed as a novel class of therapeutics?
Publication TypeJournal Article
Year of Publication2017
AuthorsWehbe, M, Leung, AWY, Abrams, MJ, Orvig, C, Bally, MB
JournalDalton Trans.
Volume46
Pagination10758-10773
Abstract

Although copper-ligand complexes appear to be promising as a new class of therapeutics{,} other than the family of copper(ii) coordination compounds referred to as casiopeinas these compounds have yet to reach the clinic for human use. The pharmaceutical challenges associated with developing copper-based therapeutics will be presented in this article along with a discussion of the potential for high-throughput chemistry{,} computer-aided drug design{,} and nanotechnology to address the development of this important class of drug candidates.

URLhttp://dx.doi.org/10.1039/C7DT01955F
DOI10.1039/C7DT01955F