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A NOVEL AND CONVENIENT CONVERSION OF CHLORINS TO PHYTOPORPHYRINS DURING THE MODIFICATION OF CHLOROPHYLL DERIVATIVES

TitleA NOVEL AND CONVENIENT CONVERSION OF CHLORINS TO PHYTOPORPHYRINS DURING THE MODIFICATION OF CHLOROPHYLL DERIVATIVES
Publication TypeJournal Article
Year of Publication1995
AuthorsMa, LF, Dolphin, D
JournalTetrahedron Letters
Volume36
Pagination7791-7794
Date PublishedOct
Type of ArticleArticle
ISBN Number0040-4039
Abstract

Chlorophyll derivatives 2a, 2b, 2c and 3 have been readily converted to their corresponding phytoporphyrins 5a, 5b, 5c in excellent yields using benzoyl chloride in DMF. This method affords a new and efficient route to prepare monovinyl porphyrins which can be used as intermediates for the further preparation of chlorophyll related petroporphyrins and regiochemically pure benzoporphyrin derivatives for use in photodynamic therapy.

URL<Go to ISI>://A1995TA55600002