Australin E Isolated from the Soft Coral Cladiella sp. Collected in Pohnpei Activates the Inositol 5-Phosphatase SHIP1.
|Title||Australin E Isolated from the Soft Coral Cladiella sp. Collected in Pohnpei Activates the Inositol 5-Phosphatase SHIP1.|
|Publication Type||Journal Article|
|Year of Publication||2010|
|Authors||Williams DE, Amlani A, Dewi AS, Patrick BO, van Ofwegen L, Mui AL, Andersen RJ|
|Journal||Australian Journal of Chemistry|
|Pagination||895 - 900|
Four new diterpenoids, australins E-H (I-IV), have been isolated from the marine soft coral Cladiella sp. collected in Pohnpei. The structures of 1-4 were elucidated by anal. of their NMR and mass spectrometry data combined with an X-ray diffraction anal. of australin E. Australin E activates the inositol 5-phosphatase SHIP1 in vitro. [on SciFinder(R)]