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New diterpenoids from the octocoral Pachyclavularia violacea collected in Papua New Guinea

TitleNew diterpenoids from the octocoral Pachyclavularia violacea collected in Papua New Guinea
Publication TypeJournal Article
Year of Publication2000
AuthorsXu, L, Patrick, BO, Roberge, M, Allen, T, van Ofwegen, LP, Andersen, RJ
JournalTetrahedron
Volume56
Pagination9031-9037
Date PublishedNov
Type of ArticleArticle
ISBN Number0040-4020
KeywordsDITERPENOIDS, ISOGRANULATIMIDE, octocoral, Pachyclavularia violacea
Abstract

Six new diterpenoids, pachyclavulariolides A (1) to F (6), with cembrane and briarane carbon skeletons have been isolated from specimens of Pachyclavularia violacea collected in Papua New Guinea. The structures of the new diterpenoids were elucidated by analysis of spectroscopic data. A single crystal X-ray diffraction analysis of pachyclavulariolide B (2) confirmed its structure. Pachyclavulariolide F (6) showed in vitro cytotoxicity. (C) 2000 Elsevier Science Ltd. All rights reserved.

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