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Meroterpenoid MAPKAP (MK2) inhibitors isolated from the Indonesian marine sponge Acanthodendrilla sp

TitleMeroterpenoid MAPKAP (MK2) inhibitors isolated from the Indonesian marine sponge Acanthodendrilla sp
Publication TypeJournal Article
Year of Publication2004
AuthorsWilliams, DE, Telliez, JB, Liu, J, Tahir, A, Van Soest, R, Andersen, RJ
JournalJournal of Natural Products
Volume67
Pagination2127-2129
Date PublishedDec
Type of ArticleArticle
ISBN Number0163-3864
Abstract

(+)-Makassaric acid (1) and (+)-subersic acid (2), new meroterpenoid inhibitors of the protein kinase MK2, have been isolated from the marine sponge Acanthodendrilla sp. collected in Indonesia. The structures of (+)-makassaric acid (1) and (+)-subersic acid (2) were determined by spectroscopic analysis.

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