|Title||Isoarenarol, a new protein kinase inhibitor from the marine sponge Dysidea arenaria|
|Publication Type||Journal Article|
|Year of Publication||2003|
|Authors||Yoo, HD, Leung, D, Sanghara, J, Daley, D, Van Soest, R, Andersen, RJ|
|Type of Article||Article|
|Keywords||AVAROL, hydroquinone, kinase inhibitor, marine sponge, Papua New Guinea, sesquiterpene|
The novel sesquiterpene hydroquinone isoarenarol (1) and the known compound arenarol (2) were isolated from extracts of the marine sponge Dysidea arenaria Bergquist as part of a search for new protein kinase inhibitors. Both 1 and 2 showed potent and selective protein kinase inhibition in vitro.
|URL||<Go to ISI>://000184898600001|