|Title||INTERACTION OF PLASMA GELSOLIN WITH TROPOMYOSIN|
|Publication Type||Journal Article|
|Year of Publication||1992|
|Authors||Koepf, EK, Burtnick, LD|
|Type of Article||Article|
|Keywords||actin, FILAMENTS, gelsolin, MUSCLE, PROTEIN, TROPOMYOSIN|
Horse plasma gelsolin labelled with benzophenone-4-isothiocyanate can be photochemically cross-linked to rabbit cardiac tropomyosin. The cross-linking proceeds with greater efficiency in calcium-containing buffers. Further evidence for interaction between these proteins is provided by retention of fluorescently labelled gelsolin on tropomyosin-agarose affinity columns and by the ability of tropomyosin to cause an increase in the fluorescence intensity of gelsolin labelled with fluorescein-5-isothiocyanate. Both of these effects require the presence of calcium ions.
|URL||<Go to ISI>://A1992JL06800013|