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Holyrines A and B, possible intermediates in staurosporine biosynthesis produced in culture by a marine actinomycete obtained from the North Atlantic Ocean

TitleHolyrines A and B, possible intermediates in staurosporine biosynthesis produced in culture by a marine actinomycete obtained from the North Atlantic Ocean
Publication TypeJournal Article
Year of Publication1999
AuthorsWilliams, DE, Bernan, VS, Ritacco, FV, Maiese, WM, Greenstein, M, Andersen, RJ
JournalTetrahedron Letters
Volume40
Pagination7171-7174
Date PublishedOct
Type of ArticleArticle
ISBN Number0040-4039
Abstract

Holyrines A (4) and B (5), two new members of the indolocarbazole class of alkaloids, have been isolated from cultures of a marine actinomycete and their structures elucidated by spectroscopic analysis. The holyrines are possible intermediates in the biosynthesis of staurosporine (1). (C) 1999 Elsevier Science Ltd. All rights reserved.

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