|Title||A glucosamine dipicolylamine conjugate of Tc-99m(I) and Re-186(I) for use in imaging and therapy|
|Publication Type||Journal Article|
|Year of Publication||2005|
|Authors||Storr, T, Fisher, CL, Mikata, Y, Yano, S, Adam, MJ, Orvig, C|
|Type of Article||Article|
|Keywords||ACID, BIOMOLECULES, COMPLEXES, RADIOPHARMACEUTICALS, RE|
The synthesis and metal complexation of a glucosamine-appended 2,2’-dipicolylamine ligand to the tricarbonyls of Tc-99m and Re-186 is described; the ligand was found to bind in a tridentate fashion with the glucosamine function remaining pendant, and the Tc-99m complex was found to exhibit exceptional stability towards in vitro ligand exchange experiments.
|URL||<Go to ISI>://000226844900003|