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Further studies toward himandrine via sequential oxidative amidation - intramolecular Diels-Alder reactions

TitleFurther studies toward himandrine via sequential oxidative amidation - intramolecular Diels-Alder reactions
Publication TypeJournal Article
Year of Publication2013
AuthorsKasahara, T, Ciufolini, MA
JournalCANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE
Volume91
Pagination82-90
Date PublishedJAN
ISSN0008-4042
Abstract

Exploratory work toward the alkaloid himandrine evaluated the directing ability of a pyrrolidine C-3 substituent in a diastereotopic group elective intramolecular Diels-Alder reaction of a spirodienone obtained by the oxidative amidation of a phenol. The study also defined a technique for the construction of ring D of the alkaloid.

DOI10.1139/cjc-2012-0340