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Fast environment-friendly ball mill-assisted deep eutectic solvent-based extraction of natural products

TitleFast environment-friendly ball mill-assisted deep eutectic solvent-based extraction of natural products
Publication TypeJournal Article
Year of Publication2016
AuthorsWang, M, Wang, J, Zhang, Y, Xia, Q, Bi, W, Yang, X, Chen, DDa Yong
JournalJOURNAL OF CHROMATOGRAPHY A
Volume1443
Pagination262-266
Date PublishedAPR 22
ISSN0021-9673
Abstract

{A fast environment-friendly extraction method, ball mill-assisted deep eutectic solvent-based extraction, was used for the extraction of natural products from plants. In this study, tanshinones were selected as target compounds to evaluate the efficiency of the developed extraction method. Under the optimized experimental conditions, cryptotanshinone (0.176 mg/g), tanshinone I (0.181 mg/g), and tanshinone II A (0.421 mg/g) were extracted from Salvia miltiorrhiza Bunge, and the developed method was found to be greener, more efficient, and faster than conventional, environmentally harmful extraction methods such as methanol-based ultrasound-assisted extraction and heat reflux extraction. The analytical performances including recovery, reproducibility (RSD

DOI10.1016/j.chroma.2016.03.061