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EFFECT OF CONTIGNASTEROL ON HISTAMINE-RELEASE INDUCED BY ANTIIMMUNOGLOBULIN-E FROM RAT PERITONEAL MAST-CELLS

TitleEFFECT OF CONTIGNASTEROL ON HISTAMINE-RELEASE INDUCED BY ANTIIMMUNOGLOBULIN-E FROM RAT PERITONEAL MAST-CELLS
Publication TypeJournal Article
Year of Publication1994
AuthorsTakei, M, Burgoyne, DL, Andersen, RJ
JournalJournal of Pharmaceutical Sciences
Volume83
Pagination1234-1235
Date PublishedSep
Type of ArticleArticle
ISBN Number0022-3549
KeywordsSPONGE, steroids
Abstract

In rat peritoneal mass cells induced by anti-immunoglobulin E (anti-IgE), contignasterol (1) inhibited histamine release in a dose-dependent manner. On the other hand, a reduction product of contignasterol (2) did not inhibit histamine release from mast cells induced by anti-IgE.

URL<Go to ISI>://A1994PF41300008