|Title||Diterpenoids from cultured Erythropodium caribaeorum|
|Publication Type||Journal Article|
|Year of Publication||2002|
|Authors||Taglialatela-Scafati, O, Deo-Jangra, U, Campbell, M, Roberge, M, Andersen, RJ|
|Type of Article||Article|
|Keywords||ELEUTHEROBIN, ERYTHROLIDES, HALICHONDRIN-B, PHARMACOPHORE, REARRANGEMENT|
[GRAPHICS] The known antimitotic agent eleutherobin and the briarane diterpenoids erythrolides A and B have been isolated from cultured specimens of Erythropodium caribaeorum in amounts,comparable to those reported from wild-harvested reef animals. The novel diterpenoid aquariolide A, having an unprecedented highly-rearranged carbon skeleton (named aquariane), has also been found. The aquariane skeleton can be formally derived from the briarane-skeleton by sequential di-pi-methane and vinyl-cyclopropane rearrangements.
|URL||<Go to ISI>://000179173700025|