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Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D

TitleDirected aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D
Publication TypeJournal Article
Year of Publication2011
AuthorsTurner, CDylan, Ciufolini, MA
JournalBEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Volume7
Pagination1475-1485
Date PublishedOCT 28
ISSN1860-5397
Abstract

This is a review of our efforts toward the synthesis of a group of natural products that display noteworthy biological activity: Fredericamycin A, nothapodytine B, and topopyrones B and D. In each case, directed aromatic functionalization methodology greatly facilitated the assembly of the key molecular subunits.

DOI10.3762/bjoc.7.171