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A direct route to 2-alkyl-4-carbethoxy-5-vinyloxazoles.

TitleA direct route to 2-alkyl-4-carbethoxy-5-vinyloxazoles.
Publication TypeJournal Article
Year of Publication2010
AuthorsZhang, J, Ciufolini, MA
JournalTetrahedron Letters
Volume51
Pagination4699 - 4701
Date Published2010///
ISBN Number0040-4039
Keywordsalkylcarboethoxy vinyloxazole prepn reaction mechanism, chloroglycinate acetylenealane cyclization
Abstract

The reaction of an α-chloroglycinate ester with the dimethylaluminum acetylide deriv. of Ph propargyl ether provides the corresponding 5-vinyloxazole, e.g., I in 40-50% yield. [on SciFinder(R)]