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DEVELOPMENT AND APPLICATIONS OF AN OXAZOLE-FORMING REACTION

TitleDEVELOPMENT AND APPLICATIONS OF AN OXAZOLE-FORMING REACTION
Publication TypeJournal Article
Year of Publication2011
AuthorsZhang, J, Coqueron, P-Y, Ciufolini, MA
JournalHETEROCYCLES
Volume82
Pagination949+
Date PublishedMAR 1
ISSN0385-5414
Abstract

We review an oxazole-forming reaction devised in our laboratory. The technique allows the facile assembly of 2,5-disubstituted-4-carbalkoxy oxazoles, including 5-amino and 5-alkenyl oxazoles. Applications of this chemistry in the total synthesis of muscoride A, siphonazoles, and other oxazole alkaloids are described.

DOI10.3987/REV-10-SR(E)3