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Chemistry 333: Spectroscopic Techniques in Organic Chemistry

Course Level: 
Third Year
Academic Year: 

1. Introduction into Organic Spectroscopy

2. Ultraviolet/Visible Spectroscopy – Theory and Applications
    i) Electron Transitions between Orbitals
    ii) Analysis of UV/Vis Spectra

3. Infrared Spectroscopy – Theory and Applications
    i) Simple Stretching Vibrations
    ii) Higher Order Vibrations
    iii) Analysis of Vibrational Banding Patterns

4. Mass Spectrometry – Theory and Applications
    i) Ionization Techniques
    ii) Mass Analyzers
    iii) Molecular Ions and High Resolution MS
    iv) Analysis of Mass Spectral Fragmentation Patterns

5. Nuclear Magnetic Resonance Spectroscopy – Theory and Applications
    i) Nuclei with Spin 1/2
    ii) The Chemical Shift Scale
    iii) Scalar Coupling between Nuclei
    iv) Analysis of 1D NMR Spectra
    v) Nuclear Overhauser Effect
    vi) Introduction to analysis of 2D NMR Spectra

6. Applications of Spectroscopic Techniques to Chemical and Biochemical Problems
    i) Use in Determining Molecular Structures from Spectra
    ii) Use in Investigating Reaction Mechanisms
    iii) Use in Protein Structure Determination

i) Required Textbook: "Introduction to Spectroscopy, Fourth Edition”, by Pavia, Lampman, Kriz, and Vyvyan. Brooks/Cole
ii) Required Workbook: "Organic Structures from Spectra, Fifth Edition" by Field, Sternhell and Kalman. John Wiley and Sons