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List of Publications

Zhang R, Li CM, Williams LK, Rempel BP, Brayer GD, Withers SG. Directed "in Situ" Inhibitor Elongation as a Strategy To Structurally Characterize the Covalent Glycosyl-Enzyme Intermediate of Human Pancreatic alpha-Amylase. Biochemistry. 2009;48:10752-64. Abstract
Tarling CA, Woods K, Zhang R, Brastianos HC, Brayer GD, Andersen RJ, et al. The search for novel human pancreatic alpha-amylase inhibitors: High-throughput screening of terrestrial and marine natural product extracts. Chembiochem. 2008;9:433-8. Abstract
Maurus R, Begum A, Williams LK, Fredriksen JR, Zhang R, Withers SG, et al. Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity. Biochemistry. 2008;47:3332-44. Abstract
Zhang R, McCarter JD, Braun C, Yeung W, Brayer GD, Withers SG. Synthesis and testing of 2-deoxy-2,2-dihaloglycosides as mechanism-based inhibitors of alpha-glycosidases. Journal of Organic Chemistry. 2008;73:3070-7. Abstract
Maurus R, Begum A, Kuo HH, Racaza A, Numao S, Andersen C, et al. Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase. Protein Sci. 2005;14:743-55. Abstract
Li CM, Begum A, Numao S, Park KH, Withers SG, Brayer GD. Acarbose rearrangement mechanism implied by the kinetic and structural analysis of human pancreatic alpha-amylase in complex with analogues and their elongated counterparts. Biochemistry. 2005;44:3347-57. Abstract
Damager I, Numao S, Chen HM, Brayer GD, Withers SG. Synthesis and characterisation of novel chromogenic substrates for human pancreatic alpha-amylase. Carbohydr Res. 2004;339:1727-37. Abstract
Numao S, Damager I, Li CM, Wrodnigg TM, Begum A, Overall CM, et al. In situ extension as an approach for identifying novel alpha-amylase inhibitors. J Biol Chem. 2004;279:48282-91. Abstract
Rydberg EH, Li CM, Maurus R, Overall CM, Brayer GD, Withers SG. Mechanistic analyses of catalysis in human pancreatic alpha-amylase: Detailed kinetic and structural studies of mutants of three conserved carboxylic acids. Biochemistry. 2002;41:4492-502. Abstract
Numao S, Maurus R, Sidhu G, Wang Y, Overall CM, Brayer GD, et al. Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase. Biochemistry. 2002;41:215-25. Abstract

Recently Added

Ross A, Soares DC, Covelli D, Pannecouque C, Budd L, Collins A, et al. Oxovanadium(IV) cyclam and bicyclam complexes: potential CXCR4 receptor antagonists. Inorg Chem. 2010;49(3):1122-32. Abstract
Delgado-Jaime MU, Mewis CP, Kennepohl P. Blueprint XAS: a Matlab-based toolbox for the fitting and analysis of XAS spectra. J Synchrotron Radiat. 2010;17(1):132-7. Abstract
Bates JI, Kennepohl P, Gates DP. Abnormal reactivity of an N-heterocyclic carbene (NHC) with a phosphaalkene: a route to a 4-phosphino-substituted NHC. Angew Chem Int Ed Engl. 2009;48(52):9844-7.
Sriskandakumar T, Petzold H, Bruijnincx PC, Habtemariam A, Sadler PJ, Kennepohl P. Influence of oxygenation on the reactivity of ruthenium-thiolato bonds in arene anticancer complexes: insights from XAS and DFT. J Am Chem Soc. 2009;131(37):13355-61. Abstract
Kennepohl P, Wasinger EC, DeBeer George S. X-ray spectroscopic approaches to the investigation and characterization of photochemical processes. J Synchrotron Radiat. 2009;16(Pt 4):484-8. Abstract
Karunakaran-Datt A, Kennepohl P. Redox photochemistry of methionine by sulfur K-edge X-ray absorption spectroscopy: potential implications for cataract formation. J Am Chem Soc. 2009;131(10):3577-82. Abstract
Martin-Diaconescu V, Kennepohl P. Effects of hyperconjugation on the electronic structure and photoreactivity of organic sulfonyl chlorides. Inorg Chem. 2009;48(3):1038-44. Abstract
Praetorius JM, Allen DP, Wang R, Webb JD, Grein F, Kennepohl P, et al. N-heterocyclic carbene complexes of Rh: reaction with dioxygen without oxidation. J Am Chem Soc. 2008;130(12):3724-5. Abstract
Getty K, Delgado-Jaime MU, Kennepohl P. Assignment of Pre-edge Features in the Ru K-edge X-ray Absorption Spectra of Organometallic Ruthenium Complexes. Inorganica Chim Acta. 2008;361(4):1059. Abstract
Getty K, Delgado-Jaime MU, Kennepohl P. An electronic rationale for observed initiation rates in ruthenium-mediated olefin metathesis: charge donation in phosphine and N-heterocyclic carbene ligands. J Am Chem Soc. 2007;129(51):15774-6. Abstract

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