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List of Publications

Offen WA, Zechel DL, Withers SG, Gilbert HJ, Davies GJ. Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis. Chem Commun. 2009:2484-6. Abstract
Ducros VM, Tarling CA, Zechel DL, Brzozowski AM, Frandsen TP, von Ossowski I, et al. Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7B E197A and E197S glycosynthase mutants. Chem Biol. 2003;10:619-28. Abstract
Zechel DL, Reid SP, Stoll D, Nashiru O, Warren RA, Withers SG. Mechanism, mutagenesis, and chemical rescue of beta-mannosidase from Cellulomonas fimi. Biochemistry. 2003;42:7195-204. Abstract
Varrot A, Tarling CA, Macdonald JM, Stick RV, Zechel DL, Withers SG, et al. Direct observation of the protonation state of an imino sugar glycosidase inhibitor upon binding. J Am Chem Soc. 2003;125:7496-7.
Ducros VM, Zechel DL, Murshudov GN, Gilbert HJ, Szabo L, Stoll D, et al. Substrate distortion by a beta-mannanase: Snapshots of the Michaelis and covalent-intermediate complexes suggest a B-2,B-5 conformation for the transition state. Angew Chem-Int Edit. 2002;41:2824-+.
Zechel DL, Reid SP, Nashiru O, Mayer C, Stoll D, Jakeman DL, et al. Enzymatic synthesis of carbon-fluorine bonds. J Am Chem Soc. 2001;123:4350-1.
Nashiru O, Zechel DL, Stoll D, Mohammadzadeh T, Warren RA, Withers SG. beta-Mannosynthase: Synthesis of beta-mannosides with a mutant beta-mannosidase. Angew Chem-Int Edit. 2001;40:417-20.
Zechel DL, Withers SG. Dissection of nucleophilic and acid-base catalysis in glycosidases. Curr Opin Chem Biol. 2001;5:643-9. Abstract
Zechel DL, Withers SG. Glycosidase mechanisms: Anatomy of a finely tuned catalyst. Accounts Chem Res. 2000;33:11-8. Abstract
Zechel DL, Mayer C, Nashiru O, Reid SP, Warren RA, Withers SG. Turbo-glycosynthases: Enhanced glycosylation activity obtained by substituting serine at the nucleophile position in retaining glycosidases. Biochemistry. 2000;39:61.

Recently Added

Ross A, Soares DC, Covelli D, Pannecouque C, Budd L, Collins A, et al. Oxovanadium(IV) cyclam and bicyclam complexes: potential CXCR4 receptor antagonists. Inorg Chem. 2010;49(3):1122-32. Abstract
Delgado-Jaime MU, Mewis CP, Kennepohl P. Blueprint XAS: a Matlab-based toolbox for the fitting and analysis of XAS spectra. J Synchrotron Radiat. 2010;17(1):132-7. Abstract
Bates JI, Kennepohl P, Gates DP. Abnormal reactivity of an N-heterocyclic carbene (NHC) with a phosphaalkene: a route to a 4-phosphino-substituted NHC. Angew Chem Int Ed Engl. 2009;48(52):9844-7.
Sriskandakumar T, Petzold H, Bruijnincx PC, Habtemariam A, Sadler PJ, Kennepohl P. Influence of oxygenation on the reactivity of ruthenium-thiolato bonds in arene anticancer complexes: insights from XAS and DFT. J Am Chem Soc. 2009;131(37):13355-61. Abstract
Kennepohl P, Wasinger EC, DeBeer George S. X-ray spectroscopic approaches to the investigation and characterization of photochemical processes. J Synchrotron Radiat. 2009;16(Pt 4):484-8. Abstract
Karunakaran-Datt A, Kennepohl P. Redox photochemistry of methionine by sulfur K-edge X-ray absorption spectroscopy: potential implications for cataract formation. J Am Chem Soc. 2009;131(10):3577-82. Abstract
Martin-Diaconescu V, Kennepohl P. Effects of hyperconjugation on the electronic structure and photoreactivity of organic sulfonyl chlorides. Inorg Chem. 2009;48(3):1038-44. Abstract
Praetorius JM, Allen DP, Wang R, Webb JD, Grein F, Kennepohl P, et al. N-heterocyclic carbene complexes of Rh: reaction with dioxygen without oxidation. J Am Chem Soc. 2008;130(12):3724-5. Abstract
Getty K, Delgado-Jaime MU, Kennepohl P. Assignment of Pre-edge Features in the Ru K-edge X-ray Absorption Spectra of Organometallic Ruthenium Complexes. Inorganica Chim Acta. 2008;361(4):1059. Abstract
Getty K, Delgado-Jaime MU, Kennepohl P. An electronic rationale for observed initiation rates in ruthenium-mediated olefin metathesis: charge donation in phosphine and N-heterocyclic carbene ligands. J Am Chem Soc. 2007;129(51):15774-6. Abstract

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