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An avenue to the sordarin core adaptable to analog synthesis

TitleAn avenue to the sordarin core adaptable to analog synthesis
Publication TypeJournal Article
Year of Publication2007
AuthorsLiang, H, Schule, A, Vors, JP, Ciufolini, MA
JournalOrganic Letters
Volume9
Pagination4119-4122
Date PublishedOct
ISBN Number1523-7060
Abstract

We describe a synthesis of ketones 3 (X = O-R or CN; Y = H or alkyl), which are useful building blocks for the preparation of analogs of the potent antifungal agent sordarin, 1. Congeners of 1 constructed from 3 should permit detailed SAR investigations of the terpenoid core of the natural product.

URL<Go to ISI>://000249987200009